What causes antibiotic resistance Kevin Wu
What if i told you there were trillions of tiny bacteria all around you it's true.Microorganisms called bacteria were some of the first life forms to appear on earth.Though they consist of only a single cell, their total biomass is greater than that of all plants and animals combined.And they live virtually everywhere on the ground, in the water, on your kitchen table, on your skin, even inside you.Don't reach for the panic button just yet.Although you have 10 times more bacterial cells inside you than your body has human cells,.
Many of these bacteria are harmless or even beneficial, helping digestion and immunity.But there are a few bad apples that can cause harmful infections, from minor inconveniences to deadly epidemics.Fortunately, there are amazing medicines designed to fight bacterial infections.Synthesized from chemicals or occurring naturally in things like mold, these antibiotics kill or neutralize bacteria by interrupting cell wall synthesis or interfering with vital processes like protein synthesis, all while leaving human cells unharmed.The deployment of antibiotics over the course of the 20th century has rendered many previously dangerous diseases easily treatable.
But today, more and more of our antibiotics are becoming less effective.Did something go wrong to make them stop working the problem is not with the antibiotics but the bacteria they were made to fight, and the reason lies in darwin's theory of natural selection.Just like any other organisms, individual bacteria can undergo random mutations.Many of these mutations are harmful or useless, but every now and then, one comes along that gives its organism an edge in survival.And for a bacterium, a mutation making it resistant to a certain antibiotic.
Gives quite the edge.As the nonresistant bacteria are killed off, which happens especially quickly in antibioticrich environments, like hospitals, there is more room and resources for the resistant ones to thrive, passing along only the mutated genes that help them do so.Reproduction isn't the only way to do this.Some can release their dna upon death to be picked up by other bacteria, while others use a method called conjugation, connecting through pili to share their genes.Over time, the resistant genes proliferate, creating entire strains of resistant super bacteria.
So how much time do we have before these superbugs take over well, in some bacteria, it's already happened.For instance, some strands of staphylococcus aureus, which causes everything from skin infections to pneumonia and sepsis, have developed into mrsa, becoming resistant to betalactam antibiotics, like penicillin, methicillin, and oxacillin.Thanks to a gene that replaces the protein betalactams normally target and bind to, mrsa can keep making its cell walls unimpeded.Other super bacteria, like salmonella, even sometimes produce enzymes like betalactams that break down antibiotic attackers before they can do any damage,.
And e.Coli, a diverse group of bacteria that contains strains that cause diarrhea and kidney failure, can prevent the function of antibiotics, like quinolones, by actively booting any invaders that manage to enter the cell.But there is good news.Scientists are working to stay one step ahead of the bacteria, and although development of new antibiotics has slowed in recent years, the world health organization has made it a priority to develop novel treatments.Other scientists are investigating alternate solutions, such as phage therapy or using vaccines to prevent infections.
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Cauldron Cure May Send MRSA Running Scared
I'm miranda savioli with today's health news.It's said 'with age comes wisdom' and as it turns out, a one thousandyearold cure might do the trick for one common, potentially deadly infection.The washington post writes that scientists in the united kingdom are bringing back a medieval recipe previously used to treat eye styes, hoping it may now treat mrsa.The brew found in a 10thcentury medicinal handbook doesn't call for eye of newt or toeoffrog, but it does require mixing cropleek, garlic, wine and cow's bile and allowing the concoction.
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